1.3 Papule

Synonymes

Papule.

Definition/Description

Focal, elevated, solid, circumscribed, palpable increase in substance of skin, sharp borders, surface usually smooth.

 

Colors: if caused by inflammation, red; if secondary to other deposits: red, brown or yellow.

 

Size: ≤ 1 cm.

Localization

May appear on entire body, for example maculo-papular exanthem.

Cours

Papules may coalesce to form plaque.

 

Papule may enlarge to form nodule.

 

May develop scales, crusts or erosion.

 

May be associated with: macule (maculo-papular), vesicle (papulo-vesicular) or pustule (papulo-pustular).

Comment / Explanation

Distinguish from nodule which is >0.5 cm.

Inflammatory papules often pruritic.

Typical Dermatoses

Multiple lesions: Drug exanthema, lichen planus, scabies, syphilis, acne.


Single lesions: Melanocytic nevus, tumors such as early nodular basal cell carcinoma.

Pathophysiology

Inflammatory infiltrate, deposits of lipids, proliferations of cells.

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